A total of 1918 loci, detected by the hybridization of 938 expressed sequence tag unigenes from 26 Triticeae cDNA libraries, were mapped to wheat homoeologous group 4 chromosomes using a set of deletion, ditelosomic, and nulli-tetrasomic lines. The 1918 EST loci were not distributed uniformly among the three group 4 chromosomes; 41, 28, and 31% mapped to chromosomes 4A, 4B, and 4D, respectively. This pattern is in contrast to the cumulative results of EST mapping in all homoeologous groups, as reported (...) elsewhere, that found the highest proportion of loci mapped to the B genome. Sixty-five percent of these 1918 loci mapped to the long arms of homoeologous group 4 chromosomes, while 35% mapped to the short arms. The distal regions of chromosome arms showed higher numbers of loci than the proximal regions, with the exception of 4DL. This study confirmed the complex structure of chromosome 4A that contains two reciprocal translocations and two inversions, previously identified. An additional inversion in the centromeric region of 4A was revealed. A consensus map for homoeologous group 4 was developed from 119 ESTs unique to group 4. Forty-nine percent of these ESTs were found to be homoologous to sequences on rice chromosome 3, 12% had matches with sequences on other rice chromosomes, and 39% had no matches with rice sequences at all. Limited homology was found between wheat ESTs on homoeologous group 4 and the Arabidopsis genome. Forty-two percent of the homoeologous group 4 ESTs could be classified into functional categories on the basis of blastX searches against all protein databases. (shrink)

The DAMA project is an observatory for rare processes and it is operative deep underground at the Gran Sasso National Laboratory of the I.N.F.N. In particular, the DAMA/LIBRA (Large sodium Iodide Bulk for RAre processes) set-up consists of highly radiopure NaI(Tl) detectors for a total sensitive exposed mass of ≃250 kg. Recent results, obtained by this set-up by exploiting the model independent annual modulation signature of Dark Matter (DM) particles, have confirmed and improved those obtained by the former DAMA/NaI experiment. (...) A model independent evidence for the presence of Dark Matter particles in the galactic halo is cumulatively obtained at 8.2 σ C.L. No systematics or side reactions able to account for the measured modulation amplitude and to contemporaneously satisfy all the many specific requirements of the signature have been found or suggested by anyone over more than a decade. An example of one of the many possible model dependent corollary quests for the candidate particles and for the related astrophysical, nuclear and particle physics scenarios is presented considering the whole cumulative exposure. Future perspectives are shortly addressed. (shrink)

The complex hexaploid wheat genome offers many challenges for genomics research. Expressed sequence tags facilitate the analysis of gene-coding regions and provide a rich source of molecular markers for mapping and comparison with model organisms. The objectives of this study were to construct a high-density EST chromosome bin map of wheat homoeologous group 2 chromosomes to determine the distribution of ESTs, construct a consensus map of group 2 ESTs, investigate synteny, examine patterns of duplication, and assess the colinearity with rice (...) of ESTs assigned to the group 2 consensus bin map. A total of 2600 loci generated from 1110 ESTs were mapped to group 2 chromosomes by Southern hybridization onto wheat aneuploid chromosome and deletion stocks. A consensus map was constructed of 552 ESTs mapping to more than one group 2 chromosome. Regions of high gene density in distal bins and low gene density in proximal bins were found. Two interstitial gene-rich islands flanked by relatively gene-poor regions on both the short and long arms and having good synteny with rice were discovered. The map locations of two ESTs indicated the possible presence of a small pericentric inversion on chromosome 2B. Wheat chromosome group 2 was shown to share syntenous blocks with rice chromosomes 4 and 7. (shrink)

This report describes the rationale, approaches, organization, and resource development leading to a large-scale deletion bin map of the hexaploid wheat genome. Accompanying reports in this issue detail results from chromosome bin-mapping of expressed sequence tags representing genes onto the seven homoeologous chromosome groups and a global analysis of the entire mapped wheat EST data set. Among the resources developed were the first extensive public wheat EST collection. Described are protocols for sequencing, sequence processing, EST nomenclature, and the assembly of (...) ESTs into contigs. These contigs plus singletons were used for selection of distinct sequence motif unigenes. Selected ESTs were rearrayed, validated by 5′ and 3′ sequencing, and amplified for probing a series of wheat aneuploid and deletion stocks. Images and data for all Southern hybridizations were deposited in databases and were used by the coordinators for each of the seven homoeologous chromosome groups to validate the mapping results. Results from this project have established the foundation for future developments in wheat genomics. (shrink)

Searches for non-paulian nuclear processes, i.e. processes normally forbidden by the Pauli–Exclusion–Principle (PEP) with highly radiopure NaI(Tl) scintillators allow the test of this fundamental principle with high sensitivity. Status and perspectives are addressed.

" Au gre des rangements a perte de vue de ma bibliotheque, j'ai fini par mettre ensemble Heraclite, Zhuangzi, Goethe, Nietzsche, Thoreau, Bachelard et Rimbaud. Leur point commun, c'est la comprehension (" prendre avec ") de la nature, qui leur donne l'image la plus sensee de l'existence : pour mesurer notre place dans l'univers, il faut d'abord entendre la place de l'univers en nous. Or cette imbrication semble oubliee voire gommee par la plupart des systemes philosophiques. Faut-il voir la quelque (...) rapport avec la destruction acceleree de la planete ou, parallelement, avec le manque d'enthousiasme general qui nous gagne? La nature, il en reste encore assez pour s'en meler. Alors, decouvrons le secret des vieilles cosmogonies et sollicitons nos auteurs un par un, les litterateurs et les visionnaires, la poignee de philosophes interesses, puis les erudits de l'ecologie si pleins de verdeur - afin de moissonner les recettes d'une attitude plus confortable. Elles risquent de surprendre. Car, a force de cerner l'intelligence du monde, on va voir que c'est un mystere a double tranchant. ". (shrink)

La Meditacion. Luis Mojica Sandoz. Editorial Universitaria, Universidad de Puerto Rico 1979, Apartado de Correos X, Rio Piedras, P. R. 00931.

Social change; Sufism; doctrines; religious aspects.

A collection of short articles on various issues from a philosophical point of view.

One of most vivid examples of deep penetration of the Koran in Sufi consciousness which result became original mystical language is The Book of Spiritual Stayings of Muhammad al-Niffari (d. 977), an obscure figure in the history of Islamic Mysticism. As the main intermediaries-obstacles between the God and the person аl-Niffari considers three stages: 1) letter (harf), or Koran, 2) knowledge (ilm), 3) gnosis (ma’rifah). All three, in opinion al-Niffari, represent the veils hiding the God from Sufi. The language of (...) this Book is paradoxical and such paradoxicality shows the abnormal condition of Sufi consciousness and impossibility of expressing his mutual relation with God. Al-Niffari tries to demonstrate that any attempt of verbal expression of Supreme Essence is doomed to failure. The mostcharacteristic of Niffari’s doctrines is the doctrine of waqfah. Waqfah is regarded as the spirit of ma’rifah: whereas ma’rifah sees God and itself also, waqfah sees only God and it is God’s presence. Ma’rifah is the limit of the utterable, but waqfah is beyond the utterable. The Book of Spiritual Stayings may be regarded as an unique interpretation experience of Koran overcoming it as obstacle on the way toward to God. Owing to it the principle of unity of Deity is preserved in its purity. (shrink)

Purpose – To review and discuss Luciano Floridi’s 2019 book The Logic of Information: A Theory of Philosophy as Conceptual Design, the latest instalment in his philosophy of information (PI) tetralogy, particularly with respect to its implications for library and information studies (LIS). Design/methodology/approach – Nine scholars with research interests in philosophy and LIS read and responded to the book, raising critical and heuristic questions in the spirit of scholarly dialogue. Floridi responded to these questions. Findings – Floridi’s PI, including (...) this latest publication, is of interest to LIS scholars, and much insight can be gained by exploring this connection. It seems also that LIS has the potential to contribute to PI’s further development in some respects. Research implications – Floridi’s PI work is technical philosophy for which many LIS scholars do not have the training or patience to engage with, yet doing so is rewarding. This suggests a role for translational work between philosophy and LIS. Originality/value – The book symposium format, not yet seen in LIS, provides forum for sustained, multifaceted and generative dialogue around ideas. (shrink)

Admettons comme hypothèse de travail pour les besoins de la discussion qui va suivre que les jugements moraux ne sont pas fondés sur des valeurs objectives, sur des propriétés naturelles des choses, des actes ou des hommes, ni sur les volontés d'un Etre supréme quelconque; admettons qu'ils relevènt ultimement de decisions individuelles, que chaque homme est sur le plan logique libre de décider des principes en vertu desquels il entend guider sa vie. La question qui se pose est la suivante: (...) ces jugements concernant ma propre vie sont-ils logiquement universalisables? Le sont-ils nécessairement? Le sont-ils parfois et à quelles conditions? En d'autres termes, le fait qu'au plan moral je valorise tel type d'action doit-il m'amener à poser que les autres “devraient” également valoriser le même type d'action? La logique du discours moral me permet-elle de poser des valeurs uniquement pour moi-méme?Ou au contraire le jugement : “je devrais agir de telle façon” entraîne-t-il le locuteur à adhérer à cet autre jugement: “X, dans des circonstances semblables, devrait agir de la même façon”? (shrink)

Abduction and metaphor are two significant concepts in cognitive science. It is found that the both mental processes are on the basis of certain similarity. The similarity inspires us to seek the answers to the following two questions: Whether there is a common cognitive mechanism behind abduction and metaphor? And if there is, whether this common mechanism could be interpreted within the unified frame of modern intelligence theory? Centering on these two issues, the paper attempts to characterize and interpret the (...) generation and evolution of scientific metaphors from the perspective of the cognitive mechanism of abductive inference. Then it interprets the common cognitive mechanism behind abduction and metaphor within Hawkins’ frame of intelligence theory. The commonality between abduction and metaphor indicates the potential to further explore human intelligence. (shrink)